PEPTIDE SYNTHESIS BY A COMBINATION OF SOLID-PHASE AND SOLUTION METHODS II SYNTHESIS OF FULLY PROTECTED PEPTIDE FRAGMENTS ON 2-METHOXY-4-ALKOXY-BENZYL ALCOHOL RESIN

DOI: 10.1016/S0040-4039(00)80406-2

Source and publish data:

Tetrahedron Letters p. 4009 - 4012 (1988)

Update date:2022-08-04

Topics:

Authors:

Mergler, M.

Nyfeler, R.

Tanner, R.

Gosteli, J.

Grogg, P.

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Article abstract of DOI:10.1016/S0040-4039(00)80406-2

The synthesis of fully protected peptide fragments by the Fmoc/ t-butyl-method on a new polymeric support is described.The fragments are obtained in good yields and high purity upon cleavage from the resin with 0.5-1percent trifluoroacetic acid in methylene chloride.

Full text of DOI:10.1016/S0040-4039(00)80406-2

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