Total Synthesis of Leukotriene B44> and Homo-LTB4 from D-Mannitol

DOI: 10.1021/jo00271a032

Source and publish data:

Journal of Organic Chemistry p. 2409 - 2416 (1989)

Update date:2022-08-04

Topics:

Authors:

Merrer, Yves Le

Gravier-Pelletier, Christine

Micas-Languin, Dominique

Mestre, Francoise

Dureault, Annie

Depezay, Jean-Claude

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Article abstract of DOI:10.1021/jo00271a032

A convergent total synthesis of leukotriene B₄ and its homo analogue has been carried out via enantiomerically pure α-hydroxy aldehydes, chiral key intermediates obtained from D-mannitol and connected at a four carbon atom interval by Wittig re

Full text of DOI:10.1021/jo00271a032

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