Stereoselective Reduction of Bicyclic Ketals. An Efficient Synthesis of (-)-(R,R)-(cis-6-Methyltetrahydropyran-2-yl)-acetic Acid, an Enantiomer of Civet Cat Constituent

DOI: 10.1246/cl.1988.927

Source and publish data:

Chemistry Letters p. 927 - 930 (1988)

Update date:2022-09-26

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Authors:

Kotsuki, Hiyoshizo

Ushio, Yasuyuki

Kadota, Isao

Ochi, Masamitsu

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Article abstract of DOI:10.1246/cl.1988.927

(-)-(R,R)-(cis-6-Methyltetrahydropyran-2-yl)acetic acid, an enantiomer of civet cat constituent, was prepared in high yield by using a stereoselective reduction of bicyclic ketals as a key step.

Full text of DOI:10.1246/cl.1988.927

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