X=Y-ZH SYSTEMS AS POTENTIAL 1,3-DIPOLES. PART 19. INTRAMOLECULAR CYCLOADDITIONS OF NON-STABILISED AZOMETHINE YLIDES GENERATED VIA THE DECARBOXYLATIVE ROUTE FROM α-AMINO ACIDS.

Article abstract of DOI:10.1016/S0040-4020(01)86199-8

Heating a range of acyclic and cyclic secondary α-amino acids with aryl aldehydes containing a proximate terminal alkene or alkyne results in consecutive condensation and decarboxylation, followed by intramolecular cycloaddition of the resultant non-stabi