
Journal of Medicinal Chemistry p. 974 - 984 (1989)
Update date:2022-08-04
Topics:
Hall, Steven E.
Han, Wen-Ching
Harris, Don N.
Hedberg, Anders
Ogletree, Martin L.
A novel bicyclic prostaglandine analogue, (1S)-<1α,2α(Z),3α,4α>-7-<3-<(hexylthio)methyl>-7-oxabicyclo<2.2.1>hept-2-yl>-5-heptenoic acid ((-)10), and its congeners were found to be potent antagonists at the TxA2 receptor.Compound (-)-10 was the only stereo
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