New pyridone, thioxopyridine, pyrazolopyridine and pyridine derivatives that modulate inflammatory mediators in stimulated RAW 264.7 murine macrophage

DOI: 10.1016/j.ejmech.2009.06.023

Source and publish data:

European Journal of Medicinal Chemistry p. 4547 - 4556 (2009)

Update date:2022-07-30

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Authors:

Hamdy, Nehal A.

Gamal-Eldeen, Amira M.

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Article abstract of DOI:10.1016/j.ejmech.2009.06.023

The reaction of 2-acetyl-5,6,7,8-tetrahydronaphthalene 1 with some aldehydes was conducted in the presence of ethyl cyanoacetate and ammonium acetate, yielded the cyanopyridones 2a-c, which react with phosphorous pentasulphide to afford the corresponding

Full text of DOI:10.1016/j.ejmech.2009.06.023

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