Synthesis and Reactivity of β-Lactones Derived from L-Threonine and Related Amino Acids

DOI: 10.1021/jo00271a013

Source and publish data:

Journal of Organic Chemistry p. 2311 - 2316 (1989)

Update date:2022-08-04

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Authors:

Pansare, Sunil V.

Vederas, John C.

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Article abstract of DOI:10.1021/jo00271a013

The synthesis and nucleophilic ring opening of optically pure N-protected α-amino-β-alkyl β-lactones was investigated.Treatment of N-BOC-L-threonine (8) and N-BOC-L-allo-threonine (9) under modified Mitsunobu conditions (Ph3P, dimethyl azodicarboxylate, -

Full text of DOI:10.1021/jo00271a013

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