
Journal of Medicinal Chemistry p. 620 - 628 (1992)
Update date:2022-09-26
Topics:
Martinez
Walker
Hirschfeld
Bruno
Yang
Maloney
A series of 1H-imidazol-1-yl- and 3-pyridyl-substituted 3,4- dihydroquinolin-2(1H)-ones was designed and synthesized as combined inhibitors of thromboxane (TXA2) synthase and cAMP phosphodiesterase (PDE) in human blood platelets. A number of st
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