3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase

DOI: 10.1021/jm00082a002

Source and publish data:

Journal of Medicinal Chemistry p. 620 - 628 (1992)

Update date:2022-09-26

Topics:

Authors:

Martinez

Walker Walker

Hirschfeld

Bruno Bruno

Yang Yang

Maloney Maloney

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00082a002

A series of 1H-imidazol-1-yl- and 3-pyridyl-substituted 3,4- dihydroquinolin-2(1H)-ones was designed and synthesized as combined inhibitors of thromboxane (TXA₂) synthase and cAMP phosphodiesterase (PDE) in human blood platelets. A number of st

Full text of DOI:10.1021/jm00082a002

Products guided by the article

Product name:2(1H)-Quinolinone, 3,4-dihydro-6-(hydroxyphenyl-3-pyridinylmethyl)-

Cas No:120067-67-6

R&D Labs maybe for 120067-67-6

ShangHai BMG Chemical Co., Ltd

Contact:+86-13524845543

Address:Room 602, no 291 sikai road shanghai
Jinhua Haoyuan Chemical CO., LTD(expird)

Contact:86-579-82465583

Address:Jinhua,Zhejiang
Hangzhou Yanshan Chemical Co.,Ltd.

Contact:86-571- 87698076

Address:Room 1001, #1 Building, Zhongtian MCC, No.2 Youzhinong, Wenyi West Road, Xihu District, Hangzhou, China
Nantong Auxin Electronic Technology Co., LTD

Contact:86-513-88760026

Address:NO.5-1, Aoxin Road, Haian Hi-tech Development Zone, Jiangsu Province, China
puyang hongda shengdao new material co.,ltd.

Contact:+86-393- 4896278

Address:No.29 East Zhongyuan Road

Relevant to this article

Photolysis of Regioisomeric α,α-Diphenyl-Substituted Diazotetrahydrofuranones: Primary and Secondary Photochemical Processes

Doi:10.1134/S1070428010100179
(2010)
New synthesis and antiparasitic activity of model 5-aryl-1-methyl-4- nitroimidazoles

Doi:10.3390/molecules14082758
(2009)
A synthesis of 6,11-disubstituted benzo[b]carbazoles

Doi:10.1139/v01-127
(2001)
Photocyclization of o-Phenoxybenzyl Alcohols in Aqueous Solution. A Simple Synthesis of 6H-Dibenzopyrans

Doi:10.1039/c39880001193
(1988)
The synthesis of single enantiomers of mycobacterial ketomycolic acids containing cis-cyclopropanes

Doi:10.1016/j.tet.2009.09.099
(2009)
Synthesis of phosphonic acid alkylesteramides as structural analogues of sulfadimidine and acetophenetidin

Doi:10.1002/ardp.19933260403
(1993)

Article Doi