Archiv der Pharmazie p. 193 - 197 (1993)
Update date:2022-09-26
Topics:
Buseck
Neidlein
The phosphonic acid alkylesteramides 19 and 36 were synthesized as structural analogues of sulfadimidine and acetophenetidin. 19 was not obtained by nucleophilic aromatic substitution, but by catalytic reduction of the corresponding nitro derivative. Condensation of the phosphonic acid diethylester 13 with aromatic aldehydes and following reduction yielded the amines 26-28.
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