Tetrahedron Letters p. 7141 - 7143 (2009)
Update date:2022-09-26
Topics:
Robertson, Jeremy
Tyrrell, Andrew J.
Chovatia, Praful T.
Skerratt, Sarah
2,2-Disubstituted pyrrolidin-3-ones are prepared in three steps from simple dihydropyran derivatives; the key spiro-N,O-acetal intermediate is a useful N-sulfonylketoiminium ion precursor. This route represents a formal synthesis of the indolizidine alkal
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