Organic phosphorus compounds. 2. Synthesis and coronary vasodilator activity of (benzothiazolylbenzyl)phosphonate derivatives

DOI: 10.1021/jm00127a021

Source and publish data:

Journal of Medicinal Chemistry p. 1528 - 1532 (1989)

Update date:2022-09-26

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Authors:

Yoshino Yoshino

Kohno Kohno

Morita Morita

Tsukamoto

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Article abstract of DOI:10.1021/jm00127a021

Structural modification and the coronary vasodilator activity of the calcium antagonist fostedil (KB-944) are described. Elimination of the benzothiazole ring or replacement of the benzothiazole ring of fostedil with other hetero rings leads to a decrease

Full text of DOI:10.1021/jm00127a021

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Product name:diethyl <<4-(benzothiazol-2-yl)phenyl>hydroxymethyl>phosphonate

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