MACROCYCLISATION EN SERIES LACTONE, THIOLACTONE et LACTAME a MOTIF ETHYLENE DIOXY. EFFETS de MATRICE du SILICIUM et de l'ETAIN

Article abstract of DOI:10.1016/S0040-4020(01)81441-1

The orientation of the macrocyclization reaction leading to the di or tetrafunctional titled compounds has been studied for 12 and 24 membered rings containing ethylene dioxy moieties.The reactions were carried out from not activated diol, dithiol or diamine and from their silyl and stannyl derivatives.They were not performed at high dilution.The intracyclic oxygen atoms had a strong influence on the orientation of the cyclisation towards the monomer.However, it was also possible to obtain the dimeric forms with yields ranging from 10 to 40percent.