SYNTHESIS OF 1-O-(1,2-DI-O-PALMITOYL-SN-GLYCERO-3-PHOSPHO)-D-MYO-INOSITOL 4,5-BISPHOSPHATE: AN ANALOGUE OF NATURALLY OCCURING (Ptd)Ins(4,5)P2

Article abstract of DOI:10.1016/S0040-4039(00)82387-4

Optically active 2,3,6-tri-O-benzyl-4,5-di-O-(trans-prop-1-enyl)-D-myo-inositol and 1,2-di-O-palmitoyl-sn-glycerol were coupled using mono- and bifunctional phosphitylating reagents to yield, after final removal of all benzyl-protecting groups the chiral title compound.