Bioorganic and Medicinal Chemistry p. 196 - 207 (2019)
Update date:2022-08-05
Topics:
Cuffaro, Doretta
Nuti, Elisa
Gifford, Valentina
Ito, Noriko
Camodeca, Caterina
Tuccinardi, Tiziano
Nencetti, Susanna
Orlandini, Elisabetta
Itoh, Yoshifumi
Rossello, Armando
Collagen degradation and proMMP-2 activation are major functions of MT1-MMP to promote cancer cell invasion. Since both processes require MT1-MMP homodimerization on the cell surface, herein we propose that the use of bifunctional inhibitors of this enzym
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