THIONATION OF IMIDAZOPYRIDINES

Article abstract of DOI:10.1007/BF00475602

Direct thionation of imidazo<4,5-b>pyridines and imidazo<4,5-c>pyridines results in the formation of their 2-thioxo derivatives, usually in high yield.The thione structure of the imidazopyridines obtained has been confirmed from their IR spectra in the solid state and in solution.The general nature of the thionation of imidazole, benzimidazole, imidazo<4,5-b>pyridine, imidazo<4,5-c>pyridine, and purine has been noted as one of the distinctive chemical properties of compounds in this series of nitrogen heterocycles.