Stereospecific Friedel-Crafts alkylation of benzene with 4-mesyloxy-L-prolines. A new synthesis of 4-phenylprolines

DOI: 10.1016/S0040-4039(00)88775-4

Source and publish data:

Tetrahedron Letters p. 1241 - 1244 (1990)

Update date:2022-09-26

Topics:

Authors:

Kronenthal

Mueller Mueller

Kuester Kuester

Kissick Kissick

Johnson Johnson

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Article abstract of DOI:10.1016/S0040-4039(00)88775-4

The reaction of benzene with cis- and trans-N-benzoyl-4-mesyloxy-L-proline (11 and 12) in the presence of AlCl₃ stereospecifically produces the corresponding trans- and cis-4-phenylproline derivatives.

Full text of DOI:10.1016/S0040-4039(00)88775-4

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