Total synthesis of (±)-pancratistatin

DOI: 10.1021/ja00195a039

Source and publish data:

Journal of the American Chemical Society p. 4829 - 4837 (1989)

Update date:2022-08-03

Topics: Stereoselective synthesis Total synthesis Organic synthesis Protecting group Reaction Conditions Chiral Auxiliary Chemistry Structural Elucidation

Authors:

Danishefsky

Lee Lee

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Article abstract of DOI:10.1021/ja00195a039

The total synthesis of the antitumor title compound has been accomplished. Among the key steps was an iodolactonization of a cyclohexadiene bearing a neighboring carboxamido group mediated by an ortho-stannylated phenol. A series of cis vicinal functional

Full text of DOI:10.1021/ja00195a039

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