Antitumor agents. 7. Synthesis and antitumor activity of novel hexacyclic camptothecin analogues

DOI: 10.1021/jm00045a007

Source and publish data:

Journal of Medicinal Chemistry p. 3033 - 3039 (1994)

Update date:2022-08-04

Topics:

Authors:

Sugimori

Ejima Ejima

Ohsuki Ohsuki

Uoto Uoto

Mitsui Mitsui

Matsumoto

Kawato Kawato

Yasuoka Yasuoka

Sato Sato

Tagawa Tagawa

Terasawa

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00045a007

Eleven novel hexacyclic and three 7,9-disubstituted pentacyclic derivatives of camptothecin were synthesized and evaluated for in vitro cytotoxic activity against P388, HOC-21, and QG-56 and in vivo antileukemic activity against P388 in mice. Hexacyclic c

Full text of DOI:10.1021/jm00045a007

Products guided by the article

Product name:3-<5-(acetylamino)-2-methoxyphenoxy>propionic acid

Cas No:121062-95-1

R&D Labs maybe for 121062-95-1

Frapp's Chemical (NFTZ) Co.,Ltd

Contact:+86-576-86137892

Address:General Chamber of Commercial Building, 159 Wanchang Middle Road, Wenling, Zhejiang, China
KA-SHING Business Trade Macau Co., Ltd.

Contact:00853-28430045

Address:23rd Floor, Block 3 La Cite, Areia Preta, Macao
Qingdao XinYongAn Chemicals Co., Ltd

Contact:+86-532-81107967

Address:Chengyang dual-port industrial park by the sea，Qingdao
Chengdu NoVi Biotechnology Co., Ltd.(expird)

Contact:13551243286/028-81458053

Address:NO.168-1-224 JULONG ROAD WUHOU DISTRICT, CHENGDU CITY,SICHUAN PROVINCE
Sichuan Highlight Fine Chemicals Co., Ltd.

Contact:+86-28-8525 1605

Address:A5-102 Airport base,388 West Airport Huang He Zhong Lu,2 Section

Relevant to this article

Towards the stereochemical assignment of natural lydiamycin A

Doi:10.1039/b922544g
(2010)
O-allylated pudovik and passerini adducts as versatile scaffolds for product diversification

Doi:10.1021/acs.joc.0c01721
(2020)
An enantioselective approach to highly substituted tetrahydrocarbazoles through hydrogen bonding-catalyzed cascade reactions

Doi:10.1021/ol1001818
(2010)
CONDENSATION REACTIONS OF α-LITHIO-IMIDAZOLINES: PREPARATION AND CONJUGATE ADDITIONS OF 2-ALKENYL-2-IMIDAZOLINES.

Doi:10.1016/S0040-4039(00)80664-4
(1988)
ANTIMICROBIAL ACTIVITY OF ALKYL AMMONIA SALTS OF SPIROARSORANES AND SUBSTITUTED BENZOARSOLES

Doi:10.1007/BF00831703
(1989)
Design, synthesis and pharmacological screening of potential anticonvulsant agents using hybrid approach

Doi:10.1016/j.ejmech.2009.09.014
(2010)

Article Doi