
Journal of Medicinal Chemistry p. 3033 - 3039 (1994)
Update date:2022-08-04
Topics:
Sugimori
Ejima
Ohsuki
Uoto
Mitsui
Matsumoto
Kawato
Yasuoka
Sato
Tagawa
Terasawa
Eleven novel hexacyclic and three 7,9-disubstituted pentacyclic derivatives of camptothecin were synthesized and evaluated for in vitro cytotoxic activity against P388, HOC-21, and QG-56 and in vivo antileukemic activity against P388 in mice. Hexacyclic c
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Doi:10.1039/b922544g
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