Synthesis p. 33 - 35 (1989)
Update date:2022-09-26
Topics:
Barluenga, Jose
Campos, Pedro J.
Canal, Gonzalo
A new general one-pot method for the high yield synthesis of secondary N-(2-alkynyl)arylamines by reaction of N-(methoxymethyl)arylamines and 1-alkynyllithium is described.This procedure has successfully been extended to the preparation of symmetrically and non-symmetrically substituted 2-butyne-1,4-diamines.
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Doi:10.1021/ja00237a064
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