Tetrahedron Letters p. 6079 - 6082 (1988)
Update date:2022-08-02
Topics:
Dellaria, Joseph F.
Santarsiero, Bernard D.
The highly stereoselective alkylation (percentde=99.6 to 97.6) o a new chiral glycine enolate synthon derived from D-2-phenylglycinol is described.Deprotection of the alkylation adducts in a one-pot, three-step procedure provides the ethyl ester hydrochloride salts of the corresponding α-amino acids with no attending racemization.
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