
Archiv der Pharmazie p. 99 - 103 (1989)
Update date:2022-08-02
Topics:
Wanner, Klaus Th.
Hoefner, Georg
The pyrrole derivatives 1, 6, and 10 react in the presence of TiCl4 with the silyl enol ether 3 to form α-substituted pyrrolidine amides stereoselectively. 6 and 10 (after HCl-addition =>11) react even at -78 deg C, the reaction of 10 exceeds that of 6 in yield and stereoselctivity.
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