BAKER'S YEAST REDUCTION OF 5-ACETYL-2-ISOXAZOLINES SYNTHESIS OF ENANTIOMERICALLY PURE 2,3-DIHYDROXY KETONES AND 1,2,4-TRIOLS

DOI: 10.1016/S0040-4039(00)82296-0

Source and publish data:

Tetrahedron Letters p. 6167 - 6170 (1988)

Update date:2022-08-03

Topics:

Authors:

Ticozzi, Calimero

Zanarotti, Antonio

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Article abstract of DOI:10.1016/S0040-4039(00)82296-0

Saccharomyces cerevisiae reduces enantioselectively racemic 5-acetyl-2-isoxazolines to 5-ethanol-2-isoxazolines in high yields and high enantiomeric excess.Subsequent ring hydrogenolysis of the alcohols thus produced leads to enantiomerically pure 2,3-dih

Full text of DOI:10.1016/S0040-4039(00)82296-0

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