Asymmetric Aldol Reactions. A Titanium Enolate Giving Very High Diastereofacial Selectivities

DOI: 10.1021/ja00197a033

Source and publish data:

Journal of the American Chemical Society p. 5722 - 5728 (1989)

Update date:2022-08-02

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Authors:

Siegel, Craig

Thornton, Edward R.

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Article abstract of DOI:10.1021/ja00197a033

Diastereofacial selectivities of 99percent can be conveniently obtained in aldol reactions of the chiral titanium enolate derived from the ketone C2H5COCH(OSiMe2-t-Bu)-c-C6H11, with representative aldehydes.The key to obtaining such selectivities is shown

Full text of DOI:10.1021/ja00197a033

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