Synthesis p. 139 - 141 (1989)
Update date:2022-07-30
Topics:
Rao, V. Sudhakar
Darbarwar, Malleshwar
A facile route to 2-methyl-4-oxo-4,5-dihydrofuro<3,2-c>quinolines 5a-d has been developed by base-catalyzed thermal rearrangement of 4-(2-propynyl)oxyquinolin-2(1H)-ones 4a-d in good yields.The propynylation of 4-hydroxyquinolin-2(1H)-ones 1a-d furnished 3,3-di(2-propynyl)-2,4-dioxo-1,2,3,4-tetrahydroquinolines 2a-d. 4-(2-propynyl)oxy-3-(2-propynyl)quinolin-2(1H)-ones 3a-d, and 4a-d.A mechanistic pathway for the formation of 5 from 4 via 6 and 7 has been described.
View MoreZhengzhou Minzhong Pharmaceutical Co.,ltd
Contact:0086-371-65797115
Address:15/F,Jiangshan Bldg, NO.126 Huanghe Road,Zhengzhou, China
Lanzhou huibang biological chemical technology Co., LTD
Contact:0931-7843964
Address:NO.2011,Yannan Road,Chengguan,
Shanghai Demand Chemical Co., ltd，China
Contact:86-021-55237578/55239122
Address:Room 3H, No.578, Yingkou Road, Yangpu District, Shanghai, China
ShangHai Original Economy-Trade Develop Co.,Ltd.,
Contact:86-21-68552131
Address:shanghai
Contact:0512-63006287
Address:no.88.YISHENG Road,etdz-WUJIANG,SUZHOU,CHINA
Doi:10.1021/om3008234
(2012)Doi:10.1002/adsc.200900599
(2009)Doi:10.1007/s10593-009-0363-y
(2009)Doi:10.3390/molecules15031513
(2010)Doi:10.1016/j.bmcl.2009.12.043
(2010)Doi:10.1021/ja01117a509
(1953)
