Synthesis p. 139 - 141 (1989)
Update date:2022-07-30
Topics:
Rao, V. Sudhakar
Darbarwar, Malleshwar
A facile route to 2-methyl-4-oxo-4,5-dihydrofuro<3,2-c>quinolines 5a-d has been developed by base-catalyzed thermal rearrangement of 4-(2-propynyl)oxyquinolin-2(1H)-ones 4a-d in good yields.The propynylation of 4-hydroxyquinolin-2(1H)-ones 1a-d furnished 3,3-di(2-propynyl)-2,4-dioxo-1,2,3,4-tetrahydroquinolines 2a-d. 4-(2-propynyl)oxy-3-(2-propynyl)quinolin-2(1H)-ones 3a-d, and 4a-d.A mechanistic pathway for the formation of 5 from 4 via 6 and 7 has been described.
View MoreChemtrade International ( China )
Contact:+86-532-86893005
Address:Rm 2-501, Huaxia Zonghe Building, No. 410 JInggangshan Road, Huangdao
Contact:86-310-8067016
Address:East Fuhua Road,Tiexi Chemical Industrial Estate,Hebei,China
Suzhou SuKaiLu Chemical Technology Co., Ltd.
Contact:+86-512-62766020
Address:Floor 4, Building 1, Xinyi Pharmaceutical Valley Wisdom Industrial Park, 415 Changyang Street, Suzhou Industrial Park, Jiangsu Province
Qingdao Pana-Life Biochem Co.,Ltd.
Contact:86-532-87683902
Address:No.967 Dalao Road, Licang Zone, Qingdao City,Shandong, China 266021
Contact:86-10-62983737; +86-10-51287608
Address:4/F Building C, 2 Shangdi Xinxi Road
Doi:10.1021/om3008234
(2012)Doi:10.1002/adsc.200900599
(2009)Doi:10.1007/s10593-009-0363-y
(2009)Doi:10.3390/molecules15031513
(2010)Doi:10.1016/j.bmcl.2009.12.043
(2010)Doi:10.1021/ja01117a509
(1953)
