Angewandte Chemie - International Edition p. 899 - 903 (2010)
Update date:2022-08-04
Topics:
Hartman, Ryan L.
Naber, John R.
Buchwald, Stephen L.
Jensen, Klavs F.
(Figure Presented) Microchemical solvent switch: A continuous-flow, multistep Heck synthesis was made possible by integrating microreactors, liquid-liquid extraction, and microfluidic distillation. The microfluidic distil-lation enabled solvent exchange from CH2CI2 in the first reaction step to N,Ndimethylformamide (DMF) in the final reaction step.
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(2010)
