Novel bis-arylsulfonamides and aryl sulfonimides as inactivators of plasminogen activator inhibitor-1 (PAI-1)

DOI: 10.1016/j.bmcl.2009.12.051

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 966 - 970 (2010)

Update date:2022-07-31

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Authors:

El-Ayache, Nadine C.

Li, Shih-Hon

Warnock, Mark

Lawrence, Daniel A.

Emal, Cory D.

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Article abstract of DOI:10.1016/j.bmcl.2009.12.051

Inactivators of plasminogen activator inhibitor-1 (PAI-1) have been identified as possible treatments for a range of conditions, including atherosclerosis, venous thrombosis, and obesity. We describe the synthesis and inhibitory activity of a novel series

Full text of DOI:10.1016/j.bmcl.2009.12.051

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