
Synthesis p. 453 - 461 (1986)
Update date:2022-09-26
Topics:
Nicolaou, K. C.
Webber, S. E.
A stereocontrolled total synthesis of six lipoxin B isomers are described.The flexible and stereoselective strategy involves Sharpless asymmetric epoxidation and pinylborane asymmetric reduction to secure the three hydroxyl-bearing stereocenters and a Wittig-type as well as palladium(0)-copper(I) coupling reactions to construct the carbon skeleton of the target molecules.
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Doi:10.1021/ja00198a091
(1989)Doi:10.1039/c2ob07071e
(2012)Doi:10.1002/poc.1608
(2010)Doi:10.1039/c3cy00240c
(2013)Doi:10.1021/jo1000109
(2010)Doi:10.1039/b925261d
(2010)