Synthesis p. 334 - 337 (1989)
Update date:2022-07-29
Topics: Deprotonation Reagent Organic synthesis Condensation Reaction Mild conditions Carboxylic Acids Dehydrative condensation
Kita, Yasuyuki
Akai, Shuji
Yamamoto, Miki
Taniguchi, Miyako
Tamura, Yasumitsu
(Trimethylsilyl)ethoxyacetylene, a stable and easy to handle dehydrating reagent, is quite effective for the title condensation to prepare ester-, lactone-, lactam-, and peptide-linkages under mild conditions.
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Doi:10.1002/hlca.19570400636
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