Journal of Organic Chemistry p. 4483 - 4485 (1989)
Update date:2022-09-26
Topics: Yield NMR spectroscopy Catalyst Isolation Stereoselective Reaction Conditions
Semmelhack, M. F.
Zhang, Nan
Starting from 5-hydroxy-1-pentenes, palladium-catalyzed intramolecular alkoxycarbonylation produces 2,5-disubstituted tetrahydrofurans in good yield.In the simplest cases, mixtures of cis- and trans-2,5-substitution are obtained.With a methyl group at C-4
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