New Leupeptin Analogues: Synthesis and Inhibition Data

DOI: 10.1021/jm00163a014

Source and publish data:

Journal of Medicinal Chemistry p. 86 - 93 (1990)

Update date:2022-08-04

Topics:

Authors:

McConnell, Rose M.

Barnes, George E.

Hoyng, Charles F.

Gunn, J. Martin

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00163a014

Syntheses of several tripeptide analogues of leupeptin containing C-terminal argininal, lysinal, or ornithinal units are presented.The synthetic analogues were tested as inhibitors of trypsin, plasmin, and kallikrein. (Benzyloxycarbonyl)-L-leucyl-L-leucyl

Full text of DOI:10.1021/jm00163a014

Products guided by the article

Product name:N^α-(benzyloxycarbonyl)-N^ε-(tert-butoxycarbonyl)-L-lysinal semicarbazone

Cas No:122314-18-5

R&D Labs maybe for 122314-18-5

LIAONING DMSO CHEMICALS CO.,LTD.

website:http://www.chinadmso.com

Contact:+86-427-6503033

Address:FLOOR 16, BLOCK A, FINANCIAL SQUARE, XINGLONGTAI DISTRICT, PANJIN CITY, LIAONING P.R. CHINA
BAODING SINO-CHEM INDUSTRY CO.,LTD

Contact:0312-5956088

Address:NO.8 FUXING ROAD,CHINA
Yangzhou Zhongbao Pharmaceutical Co.,Ltd

Contact:+86-514-88290838

Address:Jiangsu Baoying county economic develpment zone in baoying avenue91
Changsha Botaniex Inc.

Contact:(86) 731 88718666

Address:Room 1222, Unit 4, Building B, Shangcheng, No.47, Kaiyuan East Road.
Jiangxi Biochem Co.,Ltd

Contact:86-791-86629460

Address:1-6F, 118 Xinzhou road, Nanchang, Jiangxi, China

Relevant to this article

Enantioselective iridium catalyzed α-alkylation of azlactones by a tandem asymmetric allylic alkylation/aza-Cope rearrangement

Doi:10.1039/c9cc01450k
(2019)
SYNTHESIS OF (Z)-PREDOMINANT α,β-UNSATURATED NITRILES FROM ENONE CYANOHYDRIN DIETHYL PHOSPHATES: APPLICATION TO THE SYNTHESIS OF (+/-)-NUCIFERAL, (+/-)-(E)-AND -(Z)-NUCIFEROL, AND (+/-)-MANICONE

Doi:10.1039/P19880003163
(1988)
Metal-Free Direct Trifluoromethylthiolation of Aromatic Compounds Using Triptycenyl Sulfide Catalyst

Doi:10.1021/acs.orglett.1c00727
(2021)
Synthesis and reactivity of 3-amino-1H-pyrazolo[4,3-c]pyridin-4(5H)-ones: development of a novel kinase-focussed library

Doi:10.1016/j.tet.2010.02.047
(2010)
Cyanoacetanilides intermediates in heterocyclic synthesis. Part 5: Preparation of hitherto unknown 5-aminopyrazole and pyrazolo[1,5-a]pyrimidine derivatives containing sulfamoyl moiety

Doi:10.1002/jccs.200900154
(2009)
Syntheses of C-5-spirocyclic C-glycoside SGLT2 inhibitors

Doi:10.1016/j.tetlet.2010.02.024
(2010)

Article Doi