New Leupeptin Analogues: Synthesis and Inhibition Data

DOI: 10.1021/jm00163a014

Source and publish data:

Journal of Medicinal Chemistry p. 86 - 93 (1990)

Update date:2022-08-04

Topics:

Authors:

McConnell, Rose M.

Barnes, George E.

Hoyng, Charles F.

Gunn, J. Martin

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Article abstract of DOI:10.1021/jm00163a014

Syntheses of several tripeptide analogues of leupeptin containing C-terminal argininal, lysinal, or ornithinal units are presented.The synthetic analogues were tested as inhibitors of trypsin, plasmin, and kallikrein. (Benzyloxycarbonyl)-L-leucyl-L-leucyl

Full text of DOI:10.1021/jm00163a014

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Product name:N^α-(benzyloxycarbonyl)-N^ε-(tert-butoxycarbonyl)-L-lysinal semicarbazone

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