Specific Inhibition of Benzodiazepine Receptor Binding by Some N-(Indol-3-ylglyoxylyl)amino Acid Derivatives: Stereoselective Interactions

DOI: 10.1021/jm00132a004

Source and publish data:

Journal of Medicinal Chemistry p. 2514 - 2518 (1989)

Update date:2022-08-05

Topics:

Authors:

Primofiore, Giampaolo

Marini, Anna M.

Settimo, Federico Da

Martini, Claudia

Bardellini, Anna

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00132a004

Several optically active N-(indolyl-3-ylglyoxylyl)amino acid derivatives were synthesized and tested for <(3)H>flunitrazepam displacing activity in bovine brain membranes.IC₅₀ values were measured and revealed that the D form of the amino acid

Full text of DOI:10.1021/jm00132a004

Products guided by the article

Product name:(S)-2-[2-(1H-Indol-3-yl)-2-oxo-acetylamino]-3-phenyl-propionic acid ethyl ester

Cas No:122334-63-8

R&D Labs maybe for 122334-63-8

Xiamen Hisunny Chemical Co.,Ltd

website:http://www.hisunnychem.com

Contact:+86-592-3327115

Address:Unit 603,No.879,Xiahe Road,Meixin Building,Xiamen,China
Shanghai Forxine Pharmaceutical Co., Ltd.

Contact:86-021-64961699

Address:1835, Duhui Road, Minhang District, Shanghai/ 201108/ P.R. China
China Synchem Technology Co.,Ltd

website:http://www.cnsynchem.com

Contact:+86-0552-4929311

Address:No.217 Daqing Road
Junkai (Tianjin) Chemical Co., Ltd.

website:http://www.junkaichem.com

Contact:86-22-85689515

Address:Room 8-501, Building K2, The Hi-Tech Green Industrial Base, No.6, 6th Road, Hi-Tech Development Road, Tianjin Hi-Tech IndustrialPark, Tianjin, China.
ZHIJIANG ZENVA SINO COMMERCE AND TRADE CO., LTD.

website:http://www.zenvasino.com

Contact:+86-138-72658998

Address:Shibeishan Road,Zhijiang, Hubei, China

Relevant to this article

Polyarylene synthesis by cross-coupling with HOMSi reagents

Doi:10.1246/cl.2013.45
(2013)
Improved chiral olefin metathesis catalysts: Increasing the thermal and solution stability via modification of a C₁-symmetrical N-heterocyclic carbene ligand

Doi:10.1002/adsc.200900269
(2009)
Synthesis and characterization of a tin(II) bis(phosphinoyl)methanediide complex: A stannavinylidene derivative

Doi:10.1039/b922377k
(2010)
Trichothecine synthesis using organoiron complexes: Diastereoselective total syntheses of (±)-trichodiene, (±)-12,13-epoxytrichothec-9-ene, and (±)-trichodermol

Doi:10.1021/jo00280a039
(1989)
Synthesis of Nickel Nanoparticles with N-Doped Graphene Shells for Catalytic Reduction Reactions

Doi:10.1002/cctc.201500848
(2016)
Asymmetric cyanosilylation of α-keto esters catalyzed by the [Ru(phgly)₂(binap)]-C₆H₅OLi system

Doi:10.1002/ejoc.200901501
(2010)

Article Doi