Specific Inhibition of Benzodiazepine Receptor Binding by Some N-(Indol-3-ylglyoxylyl)amino Acid Derivatives: Stereoselective Interactions

DOI: 10.1021/jm00132a004

Source and publish data:

Journal of Medicinal Chemistry p. 2514 - 2518 (1989)

Update date:2022-08-05

Topics:

Authors:

Primofiore, Giampaolo

Marini, Anna M.

Settimo, Federico Da

Martini, Claudia

Bardellini, Anna

et al. et al.

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Article abstract of DOI:10.1021/jm00132a004

Several optically active N-(indolyl-3-ylglyoxylyl)amino acid derivatives were synthesized and tested for <(3)H>flunitrazepam displacing activity in bovine brain membranes.IC₅₀ values were measured and revealed that the D form of the amino acid

Full text of DOI:10.1021/jm00132a004

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Product name:(S)-2-[2-(1H-Indol-3-yl)-2-oxo-acetylamino]-3-phenyl-propionic acid ethyl ester

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