Bioorganic and Medicinal Chemistry Letters p. 6970 - 6974 (2009)
Update date:2022-08-04
Topics:
Wu, Tao
Nagle, Advait
Sakata, Tomoyo
Henson, Kerstin
Borboa, Rachel
Chen, Zhong
Kuhen, Kelli
Plouffe, David
Winzeler, Elizabeth
Adrian, Francisco
Tuntland, Tove
Chang, Jonathan
Simerson, Susan
Howard, Steven
Ek, Jared
Isbell, John
Deng, Xianming
Gray, Nathanael S.
Tully, David C.
Chatterjee, Arnab K.
Screening our in-house compound collection using a cell based Plasmodium falciparum proliferation assay we discovered a known pan-kinase inhibitor scaffold as a hit. Further optimization of this series led us to a novel benzamide scaffold which was devoid
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