A facile synthesis of lentiginosine analogues based on a highly regio- and diastereoselective allylic amination using chlorosulfonyl isocyanate

Article abstract of DOI:10.1002/ejoc.200901443

The concise synthesis of the lentiginosine analogues pyrrolidine alkaloid 2 and pyrroloazepine alkaloid 3 has been achieved from, inexpensive and. readily available D-lyxose. The key steps in the synthesis included, regio- and diastereoselective amination