Tetrahedron Letters p. 4837 - 4840 (1986)
Update date:2022-08-05
Topics:
Shea, K.J.
Svoboda, J.J.
N-(3,5-Hexadienoyl)-acrylimiates, which have been synthesized by acylation of 2-ethoxy-1-aza-1,3-butadienes with 3,5-hexadienoyl chloride, are found to undergo facile intramolecular Diels-Alder cycloadditions to afford predominately cis-hexahydroisoquinolines in good yields.
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