SYNTHESIS OF STABLE NITROXIDES WITH AMINO GROUPS AND FLUORINE ATOMS AT α-CARBON OF THE RADICAL CENTRE

Article abstract of DOI:10.1016/S0040-4039(01)80300-2

2- and 3-Imidazoline nitroxides with amino groups in the position α to the radical centre formed on oxidation of 4H-imidazole mono- and di-N-oxides in ethanolic solutions of NH3 and CH3NH3. α-Fluorinated imidazoline nitroxides have been obtained from 3-imidazoline-3-oxide derivatives by treatment with XeF2 in CH2Cl2.Nucleophilic substitution of the fluorine atom resulted in formation of aminoimidazoline nitroxides.