Application of samarium diiodide-promoted reductive carbon-nitrogen bond cleavage reaction to 3-oxopyrrolidine derivatives: Alternative synthesis of a coccinellid alkaloid, (-)-adalinine

Article abstract of DOI:10.3987/COM-09-S(S)130

Samarium diiodide-promoted reductive deamination reaction was applied to 5,5-disubstitued 3-oxopyrrolidines to provide 4,4-disubstituted 4-aminobutan-2-one derivatives, where the carbon-nitrogen bond cleavage took place at the desired position, regioselec