Tetrahedron Letters p. 6779 - 6782 (1988)
Update date:2022-08-04
Topics:
Bugg, Timothy D. H.
Abell, Chris
Coggins, John R.
Analogues of 3-dehydroshikimic acid which lack the C-4 and C-5 hydroxyl groups have been synthesised and assayed as substrates for shikimate dehydrogenase.The presence of the C-4 hydroxyl group is found to be very important for specificity, whereas the C-5 hydroxyl group is not.The enzyme exhibits enantioselectivity at C-1 and C-4 of the racemic substrate analogues.
View Morewebsite:http://www.shochem.com
Contact:021-50800795
Address:No.1043, Halei Rd, Zhangjiang Hi-Tech Park, Shanghai, Postcode 201203, China
Contact:+86-134-5286-9121
Address:Add: Wing Tuck Commercial Centre, 177-183 Wing Lok Street, Hong Kong,
Contact:17316303296
Address:240 Amboy Ave
Shanghai Send Pharmaceutical Technology Co., Ltd.
website:http://www.shsendpharma.com
Contact:021-58088081, +8613585868794
Address::Room A601, Building 1,NO. 800 Qingdai Road Pudong District Shanghai,China
Shanghai Dianyang Industry Co.,ltd
Contact:+86 21 6492 4669
Address:Chejing RD, Songjiang District, Shanghai, China
Doi:10.1021/ic100138s
(2010)Doi:10.1021/ol102216x
(2010)Doi:10.1021/acs.orglett.8b02389
(2018)Doi:10.1021/jo100115h
(2010)Doi:10.1016/j.bmc.2010.02.006
(2010)Doi:10.1021/acs.bioconjchem.5b00028
(2015)
