European Journal of Medicinal Chemistry p. 561 - 572 (1988)
Update date:2022-08-04
Topics: Monocyclic Biological Evaluation β-Lactams Synthesis
Marchand-Brynaert, Jacqueline
Laub, Ruth
Meester, Fabien de
Frere, Jean-Marie
A simple and practical methodology has been developed for the preparation of monocyclic β-lactams 6 derived from penicillin G, possessing a thiocarbonyl (6a) or a sulfonyl (6b) substituent at C(4) as potentially good leaving groups.Two phthalidyl ester pr
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