Journal of the American Chemical Society p. 8502 - 8504 (1989)
Update date:2022-08-04
Topics:
Nair, Vasu
Buenger, Greg S.
Novel congeners of the antiretroviral compound 2',3'-dideoxyadenosine (ddA) have been synthesized through metal-mediated and photochemical conversions as the key steps.These compounds are inherently more stable than ddA with respect to both glycosidic bond cleavage and deamination by adenosine deaminase.
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Doi:10.1007/BF00472393
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