ASYMMETRIC DITHIOACETALS II: A NOVEL AND VERSATILE METHOD FOR THE PREPARATION OF CHIRAL DITHIOACETALS

DOI: 10.1016/S0040-4039(00)82441-7

Source and publish data:

Tetrahedron Letters p. 6733 - 6736 (1988)

Update date:2022-07-31

Topics:

Authors:

Therien, M.

Gauthier, J. Y.

Young, R. N.

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Article abstract of DOI:10.1016/S0040-4039(00)82441-7

Reaction of aldehydes with one equivalent each of a thiol and a chiral thioacid such as (R)-(-)-α-methoxyphenylthiolacetic acid in the presence of an acidic catalyst such as ZnI2 or p-toluenesulfonic acid yields diastereomeric mixed thioacetals in good yi

Full text of DOI:10.1016/S0040-4039(00)82441-7

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