SYNTHESIS AND DNA CROSSLINKING ABILITY OF A DIMERIC ANTHRAMYCIN ANALOG

DOI: 10.1016/S0040-4039(00)80691-7

Source and publish data:

Tetrahedron Letters p. 5105 - 5108 (1988)

Update date:2022-08-04

Topics:

Authors:

Farmer, J.Dean

Rudnicki, Suzanne M.

Suggs, J.William

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)80691-7

Linked analogs of the DNA binding antibiotic anthramycin are made via nucleophilic aromatic substitution followed by reduction-cyclization.The linked compounds protect DNA from restriction endonucleases and reversibly crosslink DNA.

Full text of DOI:10.1016/S0040-4039(00)80691-7

Products guided by the article

Product name:[(S)-2-(Bis-ethylsulfanyl-methyl)-pyrrolidin-1-yl]-(5-methoxy-2-nitro-phenyl)-methanone

Cas No:123064-60-8

R&D Labs maybe for 123064-60-8

Zhonghao (dalian) Research and Design Institute of Chemical Industry Co., Ltd

Contact:+86 411 84674606

Address:201, Huangpu Road , Shahekou District, Dalian ,116023-China
Hubei Danao Pharmaceutical Co.,Ltd.

website:http://www.danaopharm.com

Contact:+86-719-5251167

Address:Fandan Road,Danjiangkou,Hubei
Tianjin Crest Pharmaceutical R&D Co., Ltd. （Tianjin Yao Technology Development Co., Ltd.）(expird)

Contact:+86-22-66211386

Address:Building B5-405, No, 80 4th Avenue, TEDA, Tianjin, China P.R. 300457
WD Silicone Co., Ltd

Contact:+86-27-87204219, +86-27-87215023

Address:2402, HuiGu Space-time Building, 8 Forest Road, East Lake Hi-Tech Development Zone
Laohekou Jinghong Chemical Co.,Ltd

Contact:+86-0710-3702747

Address:163.East，Huagong Road，Laohekou

Relevant to this article

TRANSANNULAR BOND FORMATION BETWEEN THE ANTIMONY AND THE NITROGEN ATOMS IN DIBENZ<1,5>AZASTIBOCINE SYSTEM. FORMATION OF X-Sb-X AND X-Sb-N(1+) HYPERVALENT BOND

Doi:10.1016/S0040-4039(00)82879-8
(1988)
Design, synthesis and biological evaluation of tyrosine-based hydroxamic acid analogs as novel histone deacetylases (HDACs) inhibitors

Doi:10.1016/j.bmc.2011.06.046
(2011)
Kinetic resolution of racemic secondary alcohols mediated by N-Methylimidazole in the presence of optically active acyl chlorides

Doi:10.1002/ejoc.200901075
(2010)
Structure-Based Discovery of SD-36 as a Potent, Selective, and Efficacious PROTAC Degrader of STAT3 Protein

Doi:10.1021/acs.jmedchem.9b01530
(2019)
Synthesis and antimicrobial evaluation of some new thiophene derivatives

Doi:10.1080/00397910903161652
(2010)
Isoquinoline derivatives as potent CRTH2 receptor antagonists: Synthesis and SAR

Doi:10.1016/j.bmcl.2012.03.009
(2012)

Article Doi