SYNTHESIS AND DNA CROSSLINKING ABILITY OF A DIMERIC ANTHRAMYCIN ANALOG

DOI: 10.1016/S0040-4039(00)80691-7

Source and publish data:

Tetrahedron Letters p. 5105 - 5108 (1988)

Update date:2022-08-04

Topics:

Authors:

Farmer, J.Dean

Rudnicki, Suzanne M.

Suggs, J.William

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)80691-7

Linked analogs of the DNA binding antibiotic anthramycin are made via nucleophilic aromatic substitution followed by reduction-cyclization.The linked compounds protect DNA from restriction endonucleases and reversibly crosslink DNA.

Full text of DOI:10.1016/S0040-4039(00)80691-7

Products guided by the article

Product name:[(S)-2-(Bis-ethylsulfanyl-methyl)-pyrrolidin-1-yl]-(5-methoxy-2-nitro-phenyl)-methanone

Cas No:123064-60-8

R&D Labs maybe for 123064-60-8

Xiamen Sinchem Imp.&Exp. Co.,Ltd.

website:http://www.sinchemind.com

Contact:86-592-2237696

Address::No.500, Xinlong Rd, Xiamen, China
Baoji Guokang Healthchem co.,ltd

website:http://www.gk-bio.com

Contact:86-917-3909592

Address:China
Shandong Tiantai steel-plastic Co.,Ltd

Contact:86-531-87988557

Address:Gaotang Liaocheng
Laizhou City Laiyu Chemical CO.,Ltd

Contact:+86-535-2719337/2719339

Address:Chenggang road zhuyou laizhou City Shangdong China
Kaiping Genuine Biochemical Pharmaceutical Co.,Ltd.

Contact:+86-750-2881198

Address:No.1, Xinke Road, Shatang Town, Kaiping, Guangdong Province, P.R.China

Relevant to this article

TRANSANNULAR BOND FORMATION BETWEEN THE ANTIMONY AND THE NITROGEN ATOMS IN DIBENZ<1,5>AZASTIBOCINE SYSTEM. FORMATION OF X-Sb-X AND X-Sb-N(1+) HYPERVALENT BOND

Doi:10.1016/S0040-4039(00)82879-8
(1988)
Design, synthesis and biological evaluation of tyrosine-based hydroxamic acid analogs as novel histone deacetylases (HDACs) inhibitors

Doi:10.1016/j.bmc.2011.06.046
(2011)
Kinetic resolution of racemic secondary alcohols mediated by N-Methylimidazole in the presence of optically active acyl chlorides

Doi:10.1002/ejoc.200901075
(2010)
Structure-Based Discovery of SD-36 as a Potent, Selective, and Efficacious PROTAC Degrader of STAT3 Protein

Doi:10.1021/acs.jmedchem.9b01530
(2019)
Synthesis and antimicrobial evaluation of some new thiophene derivatives

Doi:10.1080/00397910903161652
(2010)
Isoquinoline derivatives as potent CRTH2 receptor antagonists: Synthesis and SAR

Doi:10.1016/j.bmcl.2012.03.009
(2012)

Article Doi