
Tetrahedron Letters p. 5105 - 5108 (1988)
Update date:2022-08-04
Topics:
Farmer, J.Dean
Rudnicki, Suzanne M.
Suggs, J.William
Linked analogs of the DNA binding antibiotic anthramycin are made via nucleophilic aromatic substitution followed by reduction-cyclization.The linked compounds protect DNA from restriction endonucleases and reversibly crosslink DNA.
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Doi:10.1016/S0040-4039(00)82879-8
(1988)Doi:10.1016/j.bmc.2011.06.046
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(2010)Doi:10.1016/j.bmcl.2012.03.009
(2012)