Journal of Medicinal Chemistry p. 317 - 327 (1990)
Update date:2022-08-05
Topics:
Matthews, Donald P.
McCarthy, James R.
Whitten, Jeffrey P.
Kastner, Philip R.
Barney, Charlotte L.
et al.
A series of substituted 2,2-bi-1H-imidazoles and related analogues was synthesized and evaluated for inotropic activity.Structure-activity relationship studies based on a nonclassical bioisosteric approach indicated the necessity of a cyano group on one o
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