Novel 2-imidazoles as potent, selective and CNS penetrant α1A adrenoceptor partial agonists

DOI: 10.1016/j.bmcl.2008.10.066

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 6437 - 6440 (2008)

Update date:2022-08-05

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Authors:

Roberts, Lee R.

Bryans, Justin

Conlon, Kelly

McMurray, Gordon

Stobie, Alan

Whitlock, Gavin A.

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Article abstract of DOI:10.1016/j.bmcl.2008.10.066

A novel series of central nervous system (CNS) penetrant indane 2-imidazoles have been identified as potent, partial agonists of the α_1A adrenergic receptor, having good selectivity over the α_1B, α_1D and α₂ sub-

Full text of DOI:10.1016/j.bmcl.2008.10.066

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