Synthesis and Structure-Activity Relationships of New 7-- and -(Fluorohomopiperazinyl)quinolone Antibacterials

Article abstract of DOI:10.1021/jm00163a024

Some novel 6-fluoro-7-substituted-1,4-dihydro-4-oxoquinolone-3-carboxylic acids have been prepared.At the N-1 position "standard" substitution was employed with the ethyl, cyclopropyl, and p-fluorophenyl groups being used.At C-7 the introduction of some n