
Tetrahedron p. 7071 - 7082 (1992)
Update date:2022-07-30
Topics: Synthesis Oxidation Precursor applications Ylide Vicinal
Wasserman
Kuo
Attachment of carbethoxyalkyl residues to an α,β-diketo ester provides dielectrophilic species applicable to the synthesis of the vincamine alkaloids, eburnamonine and tacamonine. The required vicinal tricarbonyl aggregates were formed by oxidation of suitable ylide precursors with ozone or singlet oxygen.
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