Synthesis of N-propargyl iminosugar scaffolds for compound library generation using click chemistry

DOI: 10.1071/CH09426

Source and publish data:

Australian Journal of Chemistry p. 821 - 829 (2010)

Update date:2022-09-26

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Authors:

Wilkinson, Brendan L.

Bornaghi, Laurent F.

Lopez, Marie

Healy, Peter C.

Poulsen, Sally-Ann

Houston, Todd A.

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Article abstract of DOI:10.1071/CH09426

We have developed an efficient synthesis of N-propargyl iminosugars for use in diversity-oriented library development. Through a common, crystalline intermediate both piperidine and azepane scaffolds can be prepared with an alkyne functional group, allowi

Full text of DOI:10.1071/CH09426

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