DMAP-catalyzed cyanation of aldehydes and ketones with ethyl cyanoformate

DOI: 10.1016/j.tetlet.2010.04.123

Source and publish data:

Tetrahedron Letters p. 3547 - 3549 (2010)

Update date:2022-09-26

Topics:

Authors:

Aoki, Shohei

Kotani, Shunsuke

Sugiura, Masaharu

Nakajima, Makoto

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Article abstract of DOI:10.1016/j.tetlet.2010.04.123

The cyanation of carbonyl compounds with ethyl cyanoformate is catalyzed by 4-dimethylaminopyridine (DMAP) to afford the corresponding cyanohydrin carbonates in excellent yields. The system provides a convenient method for cyanation of carbonyl compounds

Full text of DOI:10.1016/j.tetlet.2010.04.123

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