Total synthesis of d,l-methynolide. Medium-ring sulfides by ylide ring expansion

DOI: 10.1021/ja00204a015

Source and publish data:

Journal of the American Chemical Society p. 8421 - 8430 (1989)

Update date:2022-09-26

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Authors:

Vedejs Vedejs

Buchanan

Conrad Conrad

Meier Meier

Mullins Mullins

Schaffhausen

Schwartz

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Article abstract of DOI:10.1021/ja00204a015

The sulfur-based ring expansion methodology required for the total synthesis of the title compound is described in detail. The successful route employs the ring expansion of sulfonium ylide 10 to an eight-membered sulfide 11, followed by conversion to alc

Full text of DOI:10.1021/ja00204a015

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