Chiral recognition of cinchona alkaloids at the minor and major grooves of 1,1'-binaphthyl receptors

Article abstract of DOI:10.1021/jo00090a037

A variety of chiral 1,1'-binaphthyl derivatives with one or two hydroxyl groups at either the 2,2'-(minor groove) or the 7,7'-positions (major groove) were prepared for enantioselective recognition of the cinchona alkaloids quinine and quinidine. The stud