Hypolipidemic Activity of Rifamycin Derivatives

DOI: 10.1021/jm00164a013

Source and publish data:

Journal of Medicinal Chemistry p. 552 - 560 (1990)

Update date:2022-09-26

Topics:

Authors:

Traxler, Peter

Kump, Wilhelm

Mueller, Klaus

Tosch, Werner

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Article abstract of DOI:10.1021/jm00164a013

Series of 3-piperidinyl- and 3-piperazinylrifamycins and to a certain extent 3-hydrazonorifamycins all bearing lipophilic side chains were found to exert potent hypolipidemic activity in lowering both serum cholesterol and LDL-cholesterol in rats.Starting

Full text of DOI:10.1021/jm00164a013

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